Posted by DAM on February 3, 2012 in IONISING RADIATIONS | Short Link
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Tumors, like their cell of origin, differ in their susceptibility to radiation injury. In general, a poorly differentiated tumor is more radiosensitive than a well differentiated one of the same type.

1-    Radio-sensitive tumours:

Destructive dose of radiation_causes no significant damage in adjacent normal tissues.


  • Malignant lymphoma – Seminoma of testis
  • Lymphoepithelioma -Dysgerminoma of ovary
  • Ewings tumour of bone.


    2-    Radio-responsive tumors:

    Destructive dose of radiation could do some damage to adjacent normal tissues.


  • Squamous and basal cell carcinoma.
  • Breast carcinoma.
  • Adenocarcinoma.


    Radio-resistant tumors:

    Destructive dose of radiation is equally destructive_to adjacent normal tissues.


  • Sarcomas
  • Malignant melanoma N.B.

    1 – Metastatic tumors are more radiosensitive.

    2- Poorly differentiated tumors are more radiosensitive than well-differentiated.


    Recurrence of tumours after irradiation

    Recurrent tumors after irradiation are usually radioresistant because the few resistant cells which survive transmit the property of resistance to their descendants.

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