RADIOSENSITIVITY OF TUMORS

Posted by DAM on February 3, 2012 in IONISING RADIATIONS | Short Link
Share on Facebook
Bookmark this on Digg
Post to Google Buzz
Bookmark this on Yahoo Bookmark

RADIOSENSITIVITY OF TUMORS

 

Tumors, like their cell of origin, differ in their susceptibility to radiation injury. In general, a poorly differentiated tumor is more radiosensitive than a well differentiated one of the same type.

1-    Radio-sensitive tumours:

Destructive dose of radiation_causes no significant damage in adjacent normal tissues.

Examples

  • Malignant lymphoma – Seminoma of testis
  • Lymphoepithelioma -Dysgerminoma of ovary
  • Ewings tumour of bone.

     

    2-    Radio-responsive tumors:

    Destructive dose of radiation could do some damage to adjacent normal tissues.

    Examples

  • Squamous and basal cell carcinoma.
  • Breast carcinoma.
  • Adenocarcinoma.

     

    Radio-resistant tumors:

    Destructive dose of radiation is equally destructive_to adjacent normal tissues.

    Examples:

  • Sarcomas
  • Malignant melanoma N.B.

    1 – Metastatic tumors are more radiosensitive.

    2- Poorly differentiated tumors are more radiosensitive than well-differentiated.

     

    Recurrence of tumours after irradiation

    Recurrent tumors after irradiation are usually radioresistant because the few resistant cells which survive transmit the property of resistance to their descendants.

Tags: , , , , , , , , , , , , , , , , ,

Leave a Reply

Copyright © 2010-2019 .:: I NeeD MoRe ::. All rights reserved.
This site is using the Shades theme, v2.4.1, from BuyNowShop.com.